Clinical Trial Design Publications

Publications in Clinical Trial Design

Explore the most influential research papers and scholarly works that have shaped Clinical Trial Design. Use the concept filter below to focus on a specific sub-area of research.

Clinical Trial Design

4.7K

Publications

458K

Citations

Showing yearly statistics from 2000-2026.

Page 1

	Year	Citations
Meta-analysis in clinical trials Rebecca DerSimonian, Nan M. Laird Controlled Clinical Trials Meta-analysisClinical Trial ManagementClinical TrialsClinical StudiesRandomized Controlled Trial	1986	38.5K
Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples Richard Peto, M. C. Pike, P. Armitage, British Journal of Cancer Retrospective Cohort StudyHealth SciencesHealth PolicyClinical Trial ManagementClinical Trial Analysis	1977	8.4K
SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials An‐Wen Chan, Jennifer Tetzlaff, Douglas G. Altman, Annals of Internal Medicine Clinical EndpointTrial ProtocolsClinical GuidelinesProtocol ComplianceClinical Trials	2013	7.4K
SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials A.-W. Chan, Jennifer Tetzlaff, Peter C Gøtzsche, BMJ Spirit StatementHealth PolicyClinical Trial ManagementHigh Quality ProtocolsPatient Safety	2013	6.6K
The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials David Moher, Kenneth F. Schulz, Douglas G. Altman The Lancet Meta-analysisHealth PolicyPatient SafetyClinical TrialsConsort Statement	2001	5.4K
CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomized Trials Kenneth F. Schulz Annals of Internal Medicine Reporting TrialsEpidemiologyMeta-analysisHealth PolicyClinical Trial Management	2010	3.7K
Optimal two-stage designs for phase II clinical trials Richard Simon Controlled Clinical Trials Clinical Trial ManagementClinical TrialsRandomized Controlled TrialBiostatisticsDrug Trial	1989	3.6K
Framework for design and evaluation of complex interventions to improve health Marion Campbell BMJ Complex InterventionsComplex Interventions—thatHealth PreventionEffectiveness ResearchNon-pharmacological Intervention	2000	3.4K
Consort 2010 statement: extension to cluster randomised trials Marion Campbell, Gilda Piaggio, Diana R Elbourne, BMJ Amyloid AggregationNeurochemical BiomarkersPacked AmyloidSynaptic SignalingConsort 2010	2012	3.4K
Improving the quality of reporting of randomized controlled trials. The CONSORT statement Colin B. Begg JAMA Family MedicineWide ChasmControlled TrialsConsort StatementClinical Guidelines	1996	3.3K
A Multiple Testing Procedure for Clinical Trials Peter C. O’Brien, Thomas R. Fleming Biometrics Multiple Testing ProcedurePsychiatryClinical Trial ManagementHealth PolicyTreatment Plan Evaluation	1979	3.3K
The Design and Analysis of Clinical Experiments. Michael Hills, Joseph L. Fleiss Journal of the Royal Statistical Society Series A (General) Experiment DesignPatient SafetyClinical TrialsClinical StudiesLaboratory Medicine	1987	3.3K

Page 1